Anaphylactic reactions eg, generalized rash, facial edema, dyspnea, shock; pancytopenia, agranulocytosis, hemolytic anemia, granulocytopenia, thrombocytopenia, anemia; severe hepatic dysfunction, jaundice, increased AST, ALT, lactic acid dehydrogenase, guanosine triphosphate; TEN (Lyell syndrome), oculomucocutaneous syndrome (SJS); interstitial pneumonia; interstitial nephritis.